Discovery of (2, 4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1, 3-dihydroisoindol-2-yl] methanone (AT13387), a Novel Inhibitor of the Molecular …

AJ Woodhead, H Angove, MG Carr…

Index: Journal of Medicinal Chemistry, , vol. 53, # 16 p. 5956 - 5969

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Citation Number: 131

Abstract

... Journal of Medicinal ... Medicinal Chemistry. § Biophysics. ∥ Computational Chemistry and Informatics. ⊥ DMPK. # Biology. ∞ Structural Biology. Astex Therapeutics, Ltd ... potential utility of Hsp90 inhibitors; consequently many biotechnology and pharmaceutical companies have ...