Chalcones as promising pesticidal agents against diamondback moth (Plutella xylostella): microwave-assisted synthesis and structure–activity relationship

R Kumar, P Sharma, A Shard, DK Tewary…

Index: Kumar, Rakesh; Sharma, Prabha; Shard, Amit; Tewary, Dhananjay Kumar; Nadda, Gireesh; Sinha, Arun Kumar Medicinal Chemistry Research, 2012 , vol. 21, # 6 p. 922 - 931

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Citation Number: 9

Abstract

Abstract A series of chalcones (A–CH= CH–CO–B) were synthesized under microwave irradiation, and for the first time their pesticidal activity against diamondback moth (Plutella xylostella) was evaluated to identify the promising lead structures. The structure–activity relationship (SAR) analysis revealed that electron-withdrawing substituents on ring A of chalcone provided good pesticidal agents, whereas, ring B can bear either electron- ...