Pd??Catalyzed Cross??Coupling of Aryl Carboxylic Acids with Propiophenones through a Combination of Decarboxylation and Dehydrogenation

J Zhou, G Wu, M Zhang, X Jie…

Index: Zhou, Jun; Wu, Ge; Zhang, Min; Jie, Xiaoming; Su, Weiping Chemistry - A European Journal, 2012 , vol. 18, # 26 p. 8032 - 8036

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Citation Number: 42

Abstract

Carboxylic acids are valuable as starting materials in synthetic chemistry, because of their low cost, wide diversity, and ready availability.[1] Under transition-metal catalysis, organometallic intermediates, generated by extrusion of CO2 from carboxylic acids, undergo cross-coupling reactions with other organic compounds, which represents a promising strategy to form carbonÀcarbon [2–5] and carbonÀheteroatom bonds.[6] The development ...