e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Dimethylthioxanthones formed by condensation of 2-mercaptobenzoic acid with o-, or m-xylene in sulfuric acid.

I OKABAYASHI, M KIMURA, H FUJIWARA…

Index: Okabayashi; Kimura; Fujiwara; Kato Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 6 p. 2545 - 2549

Full Text: HTML

Citation Number: 3

Abstract

Various dimethyl-substituted thioxanthones were prepared by the condensation reaction of 2- mercaptobenzoic acid and o-, m-, or p-xylene in sulfuric acid. Some of them are novel compounds (5, 11, 12, and 13). That is, from o-xylene, 1, 2-dimethyl (11)-, 2, 3-dimethyl (12)- , and 3, 4-dimethyl-thioxanthones (13) were formed in yields of 9.3, 37.1, and 12.8%, respectively. From m-xylene and p-xylene, 2, 4-dimethylthioxanthone (4) and 1, 4- ...

3,4-Dimethylbenzenethiol Structure

3,4-Dimethylben...

~%

1,2-dimethylthioxanthen-9-one Structure

1,2-dimethylthi...

2-Chlorobenzoic acid Structure

2-Chlorobenzoic acid

~%

1,2-dimethylthioxanthen-9-one Structure

1,2-dimethylthi...

2-(3,4-dimethylphenylthio)benzoic acid Structure

2-(3,4-dimethyl...

~%

2,3-dimethylthioxanthen-9-one Structure

2,3-dimethylthi...

1,2-dimethylthioxanthen-9-one Structure

1,2-dimethylthi...

o-xylene Structure

Thiosalicylic acid Structure

Thiosalicylic acid

~%

3,4-dimethylthioxanthen-9-one Structure

3,4-dimethylthi...

2,3-dimethylthioxanthen-9-one Structure

2,3-dimethylthi...

Detail

Thiosalicylic acid Structure

Thiosalicylic acid

m-Xylene Structure

~80%

2,4-dimethylthioxanthen-9-one Structure

2,4-dimethylthi...

2-(2,4-dimethylphenyl)sulfanylbenzoic acid Structure

2-(2,4-dimethyl...

~43%

2,4-dimethylthioxanthen-9-one Structure

2,4-dimethylthi...

2,4-Dimethylthiophenol Structure

2,4-Dimethylthi...

~%

2,4-dimethylthioxanthen-9-one Structure

2,4-dimethylthi...

2-Chlorobenzoic acid Structure

2-Chlorobenzoic acid

~%

2,4-dimethylthioxanthen-9-one Structure

2,4-dimethylthi...

2,2′-dithiodibenzoic acid Structure

2,2′-dithiodibe...

m-Xylene Structure

~13%

2,4-dimethylthioxanthen-9-one Structure

2,4-dimethylthi...

2-[(2,3-Dimethylphenyl)thio]benzoic acid Structure

2-[(2,3-Dimethy...

~45%

3,4-dimethylthioxanthen-9-one Structure

3,4-dimethylthi...

Benzenethiol, dimethyl- Structure

Benzenethiol, d...

~%

3,4-dimethylthioxanthen-9-one Structure

3,4-dimethylthi...

2-Chlorobenzoic acid Structure

2-Chlorobenzoic acid

~%

3,4-dimethylthioxanthen-9-one Structure

3,4-dimethylthi...

o-xylene Structure

Thiosalicylic acid Structure

Thiosalicylic acid

~%

3,4-dimethylthioxanthen-9-one Structure

3,4-dimethylthi...

2,3-dimethylthioxanthen-9-one Structure

2,3-dimethylthi...

Detail

3,4-Dimethylbenzenethiol Structure

3,4-Dimethylben...

~%

2,3-dimethylthioxanthen-9-one Structure

2,3-dimethylthi...

2-Chlorobenzoic acid Structure

2-Chlorobenzoic acid

~%

2,3-dimethylthioxanthen-9-one Structure

2,3-dimethylthi...

2-(3,4-dimethylphenylthio)benzoic acid Structure

2-(3,4-dimethyl...

~%

2,3-dimethylthioxanthen-9-one Structure

2,3-dimethylthi...

1,2-dimethylthioxanthen-9-one Structure

1,2-dimethylthi...

o-xylene Structure

Thiosalicylic acid Structure

Thiosalicylic acid

~%

3,4-dimethylthioxanthen-9-one Structure

3,4-dimethylthi...

2,3-dimethylthioxanthen-9-one Structure

2,3-dimethylthi...

Detail

2,4-Dimethylthiophenol Structure

2,4-Dimethylthi...

2-Chlorobenzoic acid Structure

2-Chlorobenzoic acid

~67%

2-(2,4-dimethylphenyl)sulfanylbenzoic acid Structure

2-(2,4-dimethyl...

2,5-DIMETHYLTHIOPHENOL Structure

2,5-DIMETHYLTHI...

~%

1,4-dimethylthioxanthen-9-one Structure

1,4-dimethylthi...

2-Chlorobenzoic acid Structure

2-Chlorobenzoic acid

~%

1,4-dimethylthioxanthen-9-one Structure

1,4-dimethylthi...

N/A Structure

~%

1,4-dimethylthioxanthen-9-one Structure

1,4-dimethylthi...

p-Xylene Structure

Thiosalicylic acid Structure

Thiosalicylic acid

~%

1,4-dimethylthioxanthen-9-one Structure

1,4-dimethylthi...