The triphenylmethyl (trityl) protecting group has enjoyed widespread use in contemporary organic synthesis since its original applications in classic carbohydrate chemistry. 1 Its lipophilic nature renders it particularly attractive for the protection of polar water soluble alcohols, including monosaccharides. A variety of methods have been employed for its introduction, including trityl triflate, 2 tritylpyridinium fluoroborate, 3 and the commercially ...
[Denton, Ross M.; An, Jie; Adeniran, Beatrice; Blake, Alexander J.; Lewis, William; Poulton, Andrew M. Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6749 - 6767]
