Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists

J Chiba, G Takayama, T Takashi, M Yokoyama…

Index: Bioorganic and Medicinal Chemistry, , vol. 14, # 8 p. 2725 - 2746

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Citation Number: 26

Abstract

... Bioorganic & Medicinal Chemistry. Volume 14, Issue 8, 15 April 2006, Pages 2725–2746. ... a Medicinal Chemistry Research Laboratory ... b New Product Research Laboratories III, Daiichi Pharmaceutical, Co., Ltd, 16-13, Kitakasai 1-chome, Edogawa-ku, Tokyo 134-8630, Japan; ...