Oxygenation of styrene by cytochrome P-450 model systems. A mechanistic study

JP Collman, T Kodadek, JI Brauman

Index: Collman, James P.; Kodadek, Thomas; Brauman, John I. Journal of the American Chemical Society, 1986 , vol. 108, # 10 p. 2588 - 2594

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Citation Number: 145

Abstract

Abstract: The manganese and iron porphyrin catalyzed oxygenation of styrene results in the production of phenylacetaldehyde as well as the expected epoxide. It is demonstrated that aldehyde is a primary product and does not result from isomerization of styrene oxide. Isotope labeling studies show that one of the fl hydrogen atoms of styrene migrates to the benzylic carbon in the course of aldehyde formation. Experiments using cis and trans ...