e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
The use of α??(aryl)??4??morpholineacetonitriles (masked acyl anion equivalents) in 1, 4??additions to α, β??unsaturated esters and nitriles. A versatile synthetic route to 6?? …
JD Albright, FJ McEvoy…
Index: Albright,J.D. et al. Journal of Heterocyclic Chemistry, 1978 , vol. 15, p. 881 - 892
Abstract The use of α-(substituted-phenyl)-4-morpholineacetonitriles in 1, 4-additions to ethyl acrylate, ethyl crotonate, methyl α-methylacrylate, acrylonitrile, methylacrylonitrile, crotononitrile and cinnamonitrile was studied. A convenient route to 6-aryl-4, 5-dihydro-3 (2H) pyridazinones from aryl aldehydes and heterocyclic aldehydes was developed.
