Chemoenzymatic synthesis of a series of 4-substituted glutamate analogues and pharmacological characterization at human glutamate transporters subtypes 1-3

S Alaux, M Kusk, E Sagot, J Bolte…

Index: Bellamy, Anthony J.; Kerr, John B.; McGregor, CChristopher J.; MacKirdy, Iain S. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982 , p. 161 - 168

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Citation Number: 35

Abstract

... J. Med. Chem. ... Data are taken from ref 8. b The I max value of 1a at EAAT1 was 80 ± 5% of the I max for (S)-Glu. c The I max values of 1j at EAAT1 and EAAT2 were 78 ± 6% and 90 ± 4%, respectively, of the I max values for (S)-Glu. ...