Synthesis of Fatty Acids with Smooth Muscle Stimulant Activity

E Crundwell, MA Pinnegar…

Index: Crundwell,E. et al. Journal of Medicinal Chemistry, 1965 , vol. 8, p. 41 - 45

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Citation Number: 8

Abstract

12-Hydroxyheptadec-trans-10-enoic acid has been synthesized bv reduction of the corresponding acetylenic derivative-7th lithium in liquid ammonia at room temperature after pretreatment with lithium hydride to avoid hydrogenolysis. This acid, which represents a ...