Chemistry Letters

Convenient synthesis of 1-aza-3-thiabicyclo (3.1. 0) hexanes from L-cysteine.

T Takata, M Kuo, Y Tamura, Y Kabe, W Ando

Index: Takata, Toshikazu; Kuo, Mingjung; Tamura, Yoshiharu; Kabe, Yoshio; Ando, Wataru Chemistry Letters, 1985 , p. 939 - 942

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Citation Number: 2

Abstract

Synthesis of optically active 2-substituted and unsubstituted 1-aza-3-thiabicyclo [3, 1.0] hexanes are accomplished By intramolecular cyclization of 4-hydroxymethylthiazolidines which are prepared By the reaction of L-cysteine methyl ester with appropriate aldehydes followed By reduction of ester function.