Pyrazolone Derivatives: Synthesis, Anti-inflammatory, Analgesic, Quantitative Structure–Activity Relationship and in Vitro Studies

FAF Ragab, NM Abdel-Gawad, HH Georgey…

Index: Chemical and Pharmaceutical Bulletin, , vol. 61, # 8 p. 834 - 845

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Citation Number: 6

Abstract

... Therefore, synthetic approaches based upon chemical modification of NSAIDs were taken with the aim of improving NSAID safety profile.7–10) The core pyrazolone structure generally attracted wide- spread attention ... Experimental Chemistry All chemicals were purchased ...