HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase

J Evenäs, F Edfeldt, M Lepistö, N Svitacheva…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 5 p. 1315 - 1321

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Citation Number: 6

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... d Department of Medicinal Chemistry, DMPK and Biology, BioDuro, Life Science Park Road Bld 2, Beijing 102206, PR China. Received 25 November 2013, Revised 18 January 2014, Accepted 20 January 2014, Available online 28 ...