Résumé Ring opening of the glycidonitriles (IIa-e) by HF/pyridine leads to the fluorocyanohydrins (IIIa-e). Treatment of the nitriles (IIIa-e) with ammonia in methanol the α- amino-β-fluoro nitriles (IVa-e) which upon acidic hydrolysis afford theβp-fluoro-α-amino acids (Va-e) in good overall yield.
