Highly regioselective Heck couplings of α, β-unsaturated tosylate and mesylate derivatives with N-acyl N-vinylamines and vinyl ethers were achieved. Several 2-alkoxy-1, 3-dienes and 2-acylamino-1, 3-butadienes were synthesized in good yields using 1.5 mol% of Pd2 (dba) 3, 3 mol% of DPPF, and diisopropylethylamine in dioxane. When working with α, β- unsaturated ketones and esters, this method provides a less costly alternative to similar ...
