e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis of 2, 4-disubstituted thiazoles and selenazoles as potential antitumor and antifilarial agents. 1. Methyl 4-(isothiocyanatomethyl) thiazole-2-carbamates,- …
Methyl 4-(isothiocyanatomethy1) thiazole-2-carbamate and methyl 4-(isothiocyanatomethyl) sel-enazole-2-carbamate have been prepared via chemical transformations involving 2- amino-4-(chloromethy1) thiazole (1) and 2-amino-4-(chloromethyl) selenazole (2), respectively, as starting materials. The homoanalog, methyl 4-(2-isothiocyanatoethyl) thiazole-2-carbamate, was prepared from (2-aminothiazol-4-y1) acetic acid. All ...
