Indolizines. 2. Preparation of 1-and 3-indolizinols and their esters

DH Wadsworth, SL Bender, DL Smith…

Index: Wadsworth, Donald H.; Bender, Steven L.; Smith, Douglas L.; Luss, Henry R.; Weidner, Charles H. Journal of Organic Chemistry, 1986 , vol. 51, # 24 p. 4639 - 4644

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Citation Number: 23

Abstract

2, 3-Diarylcyclopropenones react smoothly with pyridine and substituted pyridines in a variety of solvents to produce 1-and/or 3-indolizinols. The regioisomeric indolizines were characterized by X-ray crystallography of their acetate detivatives. The synthesis and spectroscopic properties of a number of indolizinols and their ester derivatives are described.