Stereoselective synthesis of unsaturated and functionalized l-NHBoc amino acids, using Wittig reaction under mild phase-transfer conditions

…, J Bayardon, MJ Ondel-Eymin, S Jugé

Index: Fowler, Lindsay S.; Thomas, Lynne H.; Ellis, David; Sutherland, Andrew Chemical Communications, 2011 , vol. 47, # 23 p. 6569 - 6571

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Citation Number: 17

Abstract

... cross-coupling reactions.(9) Furthermore, these compounds are often used in peptide chemistry to confer ... from l-aspartic acid 5, according to modified literature procedures with 75–98% chemical yield by ... a Reactions were performed at 90 °C during 15 h in 1.5 mL of solvent and ...