Alkanes to carboxylic acids in aqueous medium: metal-free and metal-promoted highly efficient and mild conversions

MV Kirillova, AM Kirillov, ML Kuznetsov…

Index: Kirillova, Marina V.; Kirillov, Alexander M.; Kuznetsov, Maxim L.; Silva, Jose A. L.; Frausto Da Silva, Joao J. R.; Pombeiro, Armando J. L. Chemical Communications, 2009 ,  # 17  p. 2353 - 2355

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Citation Number: 36

Abstract

A convenient and clean route to transform, in aqueous medium, various alkanes to carboxylic acidsvia single-pot carboxylation with CO and water, under mild conditions, has been achieved, proceeding efficiently and selectively even without any metal catalyst and any acid additive, at low temperatures; the relevant hydroxylating role of H2O and radical mechanisms are disclosed by radical-trap, H218O and DFT studies.