Hydroxy substituted nitrogen heterocycles containing five- and six-membered rings are well known in nature and are components of many compounds with valuable pharmacological properties. 1., and For instance, these N-substituted pyrrolidinones are of interest for the treatment of brain insufficiencies and as cognition activators. 2 In view of their low toxicities these have recently attracted much attention in the pharmaceutical arena. 3., , , , , , and In addition, ...