The Journal of organic chemistry

Asymmetric Synthesis of [2, 3-13C2, 15N]-4-Benzyloxy-5, 6-diphenyl-2, 3, 5, 6-tetrahydro-4 H-oxazine-2-one via Lipase TL-Mediated Kinetic Resolution of Benzoin: …

Y Aoyagi, A Iijima, RM Williams

Index: Sinclair, Peter J.; Zhai, Dongguan; Reibenspies, Joseph; Williams, Robert M. Journal of the American Chemical Society, 1986 ,  vol. 108,  # 5  p. 1103 - 1104

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Citation Number: 27

Abstract

Lipase TL-mediated kinetic resolution of benzoin proceeded to give the corresponding optically pure (R)-benzoin (R)-1. On the other hand,(S)-benzoin O-acetate (S)-7 could be hydrolyzed without epimerization to give (S)-benzoin (S)-1 under alkaline conditions.