A Total Synthesis of FK-5061

RE Ireland, JL Gleason, LD Gegnas…

Index: Journal of Organic Chemistry, , vol. 61, # 20 p. 6856 - 6872

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Citation Number: 78

Abstract

... The Journal of Organic Chemistry. ... J. Org. Chem. ... In addition to its interesting biological properties, FK-506 presents a significant challenge to the synthetic organic chemist. Total syntheses of FK-506 have been completed by Merck 4 in 1989 and by Schreiber 5 in 1990. ...

Rapid synthesis of 11 C-labeled FK506 for positron emission ...

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Total synthesis of FK506 and an FKBP probe reagent,[C (8), C...

[Nakatsuka, Masashi; Ragan, John A.; Sammakia, Tarek; Smith, David B.; Uehling, David E.; Schreiber, Stuart L. Journal of the American Chemical Society, 1990 , vol. 112, # 14 p. 5583 - 5601]

Total synthesis of FK506 and an FKBP probe reagent,[C (8), C...

[Journal of the American Chemical Society, , vol. 112, # 14 p. 5583 - 5601]

Total synthesis of FK-506. Part 2: Completion of the synthes...

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