A simple and effective method for the preparation of benzoxazolones from nitroarenes or aryl halides is described. Partial reduction of a nitro group in the presence of a chloroformate followed by a microwave-assisted rearrangement/ring closure sequence provides a convenient and practical procedure to prepare this important pharmacophore. Rearrangement precursors were also accessed from aryl halides through transition-metal- ...
![methyl 2-oxobenzo[d]oxazole-3(2H)-carboxylate Structure](https://image.chemsrc.com/caspic/319/17280-89-6.png)