Synthesis and anti-BVDV activity of novel δ-sultones in vitro: implications for HCV therapies

…, LJ Zhao, HF Liu, D Zhao, J Luo, XP Xie, WS Liu…

Index: Xu, Hai-Wei; Zhao, Ling-Jie; Liu, Huan-Fei; Zhao, Dan; Luo, Jiao; Xie, Xiao-Ping; Liu, Wen-Sheng; Zheng, Jia-Xin; Dai, Gui-Fu; Liu, Hong-Min; Liu, Long-Hua; Liang, Yi-Bo Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 10 p. 2388 - 2391

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Citation Number: 6

Abstract

Abstract In this study we report the synthesis and activity against bovine viral diarrhea virus (BVDV) of a novel series of bicycle δ-sultones containing γ-lactones. BVDV is responsible for major losses in cattle. Some of the synthesized δ-sultones showed pronounced anti- ...