Synthetic Communications

An Unusual S-and N-Alkylation of Mercapto Substituted Heterocycles With O, O-Dialkyl Chlorophosphate/Thiophosphate

BR Rani, UT Bhalerao, MF Rahman

Index: Rani, B. Radha; Bhalerao, U.T.; Rahman, M.F. Synthetic Communications, 1990 , vol. 20, # 19 p. 3045 - 3052

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Citation Number: 11

Abstract

Abstract: The reaction of different mercapto substituted heterocycles with 0.0-dialkyl chlorphosphate or thiophosphates, gave the corresponding S- and N- alkylated derivatives instead of the expected phosphorylated products. ... In this paper we describe the unusual products formed with ... A typical experimental procedure involves the reaction of ... 2-mercapto benzothiazole6 (1. 0.005 mol) with o,o-dimethyl ... K2C03 (0.01 moll in dry acetone (50 ml) for 12 hrs at reflux