Chlorinated arenes and hetarenes occur in a number of natural products and are lead structures in medicinal chemistry (examples of pharmacologically active chlorinated natural products and drugs include griseofulvin [1–7] and dihydronidulin [8]). In fact, in many cases, they show better pharmacological activities than their chloride-free derivatives (for an example from our laboratory, see [9, 10]). Chloroarenes and chlorohetarenes are building blocks in ...
