The greater reactivity of substituents in the 4-position of quinazoline as compared with similar or like substituents in the 2-position has been demonstrated in previous papers. When benzoylene urea (2, 4-diketotetrahydroquinazoline) is alkylated with alkyl iodides in the presence of caustic alkalies a corresponding difference in the reactivities of the two imino hydrogen atoms present in this substance is noticed, the alkyl group invariably ...
