Abstract: Addition of lithiated methoxyallene 2 to imines provided the expected allenyl amines in good yield. These could be cyclized with base or with silver nitrate to a variety of 2, 5-dihydropyrrole derivatives. Selected examples describe their conversion to pyrrolidin-3- ones or 3-methoxypyrroles. Most importantly, this [3+ 2] cyclization method could also be applied to the synthesis of 2, 5-disubstituted derivatives such as 26-28 and also to the ...
