Preparation of 3-(6-Methoxynaphthyl-2)-2-cyclohexen-1-one and Related Compounds

FC Novello, ME Christy

Index: Novello; Christy Journal of the American Chemical Society, 1953 , vol. 75, p. 5431

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Citation Number: 8

Abstract

compounds, 11-VII, which were of interest in view of the estrogenic activity of l-ethyl-2-(4- hydroxyphenyl)-6-hydroxy-1, 2, 3, 4-tetrahydronaphthalene and l-methyl-2-(4- hydroxyphenyl)-6-methoxy-3, 4-dihydronaphthalene. 2 Synthesis of I was accomplished by condensation between 2-(p-dimethylaminopropionyl)-6-rnethoxynaphthalene hydrochloride and acetoacetic ester in the presence of alcoholic potassium hydroxide. Demethylation to ...