Tetrahedron letters

The synthesis of D, L-phosphotryptophan

SF Chen, SD Kumar, M Tishler

Index: Shu Feng Chen; Kumar, Shiv D.; Tishler, Max Tetrahedron Letters, 1983 , vol. 24, # 49 p. 5461 - 5464

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Citation Number: 14

Abstract

c-amino phosphonic acid analogs of essential amino acids have been synthesized ', several analogs have not been made. Since these phosphorus containing amino acids may be regarded as isosteres of u-amino acids, our objective is to prepare them and the related phosphinic acids and to determine whether they may be of biological consequence. We now wish to report a new synthesis of phosphotryptophan. A very different, somewhat more ...