Abstract Iodinated and radioiodinated analogs of propranolol and N, N-dimethylpropranolol were synthesized wherein an iodophenyl moiety replaced the naphthalene ring of the parent drug. These new compounds were evaluated not only for their β-adrenergic blocking and antiarrhythmic activities but also for their ability to accumulate selectively in myocardial tissue. Like propranolol, the iodinated analogs displayed comparable β-blocking and ...
![2-[(2-iodophenoxy)methyl]oxirane Structure](https://image.chemsrc.com/caspic/260/75746-33-7.png)
