Total synthesis of (±)-erythrocarine using dienyne metathesis

K Shimizu, M Takimoto, Y Sato, M Mori

Index: Shimizu, Kazuya; Takimoto, Masanori; Sato, Yoshihiro; Mori, Miwako Journal of Organometallic Chemistry, 2006 , vol. 691, # 24-25 p. 5466 - 5475

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Citation Number: 23

Abstract

Total Synthesis of (±)-erythrocarine was achieved using ruthenium-catalyzed dienyne metathesis as a key step. A tetrahydroisoquinoline skeleton having tetrasubstituted carbon center was constructed using our method, that is, carbon dioxide and an alkyl group were introduced onto an alkyne having a heteroatom in a tether using the nickel complex to produce α, β-unsaturated carboxylic acid and then isoquinoline skeleton was constructed ...