Several 1-alkyl-2-methylazetidin-3-ones were prepared in good yield by the hydride- induced cyclization of the corresponding β-bromo-α, α-dimethoxyketimines, the resulting 3, 3- dimethoxyazetidines being hydrolyzed by acid. Imination of these 1, 2-disubstituted azetidin- 3-ones, followed by alkylation under kinetic control conditions resulted in regioisomeric mixtures of 2, 4-and 2, 2-dialkylated compounds. Analytical samples of the major 2, 4- ...
