Palladium (II)/copper halide/solvent combination for selective intramolecular domino reactions of indolecarboxylic acid allylamides: An Unprecedented arylation/ …

…, EM Beccalli, E Borsini, S Galli, G Lanza…

Index: Broggini, Gianluigi; Barbera, Vincenzina; Beccalli, Egle M.; Borsini, Elena; Galli, Simona; Lanza, Giuseppe; Zecchi, Gaetano Advanced Synthesis and Catalysis, 2012 , vol. 354, # 1 p. 159 - 170

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Citation Number: 35

Abstract

Abstract Intramolecular oxidative palladium-catalyzed reactions of indolylallylamides in the presence of the couple bis (acetonitrile) palladium dichloride and copper (II) halide are described. Starting from 2-and 3-indolylallylamides and involving in both cases the C-3 position of the indole nucleus, variously substituted β-carbolinones were obtained by arylation/halogenation, arylation/esterification or arylation/carboalkoxylation processes. ...