Journal of fluorine chemistry

Convenient preparation of difluoromethylene-functionalized compounds from chlorodifluoroacetic acid

M Yoshida, Y Morinaga, M Iyoda

Index: Yoshida, Masato; Morinaga, Yoshihiro; Iyoda, Masahiko Journal of Fluorine Chemistry, 1994 , vol. 68, # 1 p. 33 - 38

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Citation Number: 17

Abstract

Abstract A convenient route for the synthesis of difluoromethylene-functionalized compounds from chlorodifluoroacetic acid has been investigated. Bis (chlorodifluoroacetyl) peroxide, which was synthesized from chlorodifluoroacetic acid via its acid anhydride, was found to be a good reagent for the chlorodifluoromethylation of electron-rich aromatic compounds and olefins. The chlorine atom of the chlorodifluoromethylated compounds, ...