Tetrahedron letters

Reaction of 2-nitroso-2-methyl propane with formaldehyde, glyoxylate and glyoxylic acid

V Pilepić, S Uršić

Index: Pilepic, Viktor; Ursic, Stanko Tetrahedron Letters, 1994 , vol. 35, # 40 p. 7425 - 7428

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Citation Number: 20

Abstract

Abstract 2-nitroso-2-methyl propane reacts with formaldehyde, glyoxylate, glyoxylic, pyruvic and phenylglyoxylic acid giving the corresponding Nt-butyl hydroxamic acids. These reactions involve formation of the dipolar addition intermediates and 2-nitroso-2-methyl propane acts as a nucleophile in the reaction step in which these intermediates are formed.