Antiradiation agents. Substituted 2-pyridyloxy and 2-quinolyloxy derivatives of S-2-(alkylamino) ethyl hydrogen thiosulfates and 3-alkylthiazolidines and substituted 2- …

RD Westland, RA Cooley Jr, JL Holmes…

Index: Westland; Cooley Jr.; Holmes; Hong; Lin; Zwiesler; Grenan Journal of medicinal chemistry, 1973 , vol. 16, # 4 p. 319 - 327

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Citation Number: 18

Abstract

Substituted 2-pyridyloxy and 2-quinolyloxy derivatives of S-2-(alkylamino) ethyl hydrogen thiosulfates (Table II), 3-alkylthiazolidines (Table V), and substituted 2-pyridyloxy derivatives of 24alkylamino)-ethanethiols (Table 111) and corresponding disulfides (Table IV) were synthesized as antiradiation agents by the appropriate aziridine ring-opening reactions of substituted 2-([(1-aziridiny1) alkylloxy) pyridines and-quinolines. 5-Substituted 2- ...