Binuclear pyrazoles. I. Synthesis and cytotoxic activity of 1, 1'-dibenzyl and 1, 1'-dihydroxymethyl 4, 4'-bispyrazoles.

A CUADRO, J ELGUERO, P NAVARRO

Index: Cuadro; Elguero; Navarro Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 6 p. 2535 - 2540

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Citation Number: 44

Abstract

From 3, 3', 5, 5'-tetramethyl-4, 4'-bis-1 H-pyrazole, 3, 3', 5, 5'-tetramethyl-4, 4'-methylenebis-1 H-pyrazole and 4, 4'-methylenebis-1 H-pyrazole, the corresponding 1, 1'-dibenzyl and 1, 1'- dihydroxymethyl derivatives have been obtained. Benzylation of 1H-bispyrazoles was