Abstract Asymmetric biaryl Suzuki coupling reactions were performed with various aryl-or naphthylhalide-bearing enantiomerically pure benzylic alcohols and aryl-or naphthylboronic acids (or esters). The stereogenic benzylic alcohol was introduced by diastereoselective reduction of the arylhalide bearing a β-keto sulfoxide. In the presence of Pd (OAc) 2/CsF and dppf or PPh 3 excellent yields and atropodiastereoselectivities were obtained. The ...
