Studies on topical antiinflammatory agents. III. Synthesis of 17. ALPHA.-acyloxy-9. ALPHA.-fluoro-11. BETA.-hydroxy-16. BETA.-methyl-1, 4-pregnadiene-3, 20-dione …

三口守公， 池本知之， 田口稔， 樋口昭平…

Index: Chemical and Pharmaceutical Bulletin, , vol. 37, # 12 p. 3286 - 3293

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Abstract

... Chemistry The Ill-sulfide derivatives of betamethasone 17-esters listed in Tables I—lV were prepared by the methods shown in Chart 1 ... IV(2 —4,6~ 10,12 f23, 252639459) VI(60~73) (1,5,11,24) Chart 1 © 1989 Pharmaceutical Society of ... The chemical shifts are given in (3 (ppm). ...