A fast-response, highly sensitive and specific organoselenium fluorescent probe for thiols and its application in bioimaging

B Tang, L Yin, X Wang, Z Chen, L Tong…

Index: Tang, Bo; Yin, Lingling; Wang, Xu; Chen, Zhenzhen; Tong, Lili; Xu, Kehua Chemical Communications, 2009 , # 35 p. 5293 - 5295

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Citation Number: 56

Abstract

Thiols, an interesting family of compounds, are considered to be related to a wide range of biochemical events, including redox-, methyl transfer- and CoA-related reactions. 1 Intracellular thiols such as glutathione (GSH), cysteine (Cys), and homocysteine (Hcy) play a crucial role in maintaining biological redox homeostasis. 2 The levels of intracellular thiols change dramatically in response to oxidative stress, which has been associated with a number of diseases, including ...