Tetrahedron Letters

Synthesis of multisubstituted furans via copper-catalyzed intramolecular O-vinylation of ketones with vinyl bromides

L Chen, Y Fang, Q Zhao, M Shi, C Li

Index: Chen, Liqun; Fang, Yewen; Zhao, Qiwu; Shi, Min; Li, Chaozhong Tetrahedron Letters, 2010 , vol. 51, # 28 p. 3678 - 3681

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Citation Number: 10

Abstract

Furans are important structural motifs in a number of biologically active natural products and medicinal agents such as nakadomarin A 1 and Sumiki's acid. 2 They are also versatile building blocks in organic synthesis. 3 Preparations of furans have long been an important topic in organic chemistry and continue to be actively pursued. 4 Conventional methods include the Feist–Bénary reactions and the Paal–Knorr furan synthesis. 3 The recently developed transition metal ...