Bioorganic & medicinal chemistry

New repertoire of 'donor-two-acceptor'NIR fluorogenic dyes

E Kisin-Finfer, D Shabat

Index: Kisin-Finfer, Einat; Shabat, Doron Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 12 p. 3602 - 3608

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Citation Number: 14

Abstract

Dye molecules with various fluorescent wavelengths are widely used for diagnostic and optical imaging applications. Accordingly, there is a constant demand for fluorogenic dyes with new properties. We have recently developed a novel strategy for the design of long- wavelength fluorescent dyes with a turn-ON option. The design is based on a donor-two- acceptor π-electron system that can undergo an internal charge transfer to form a new ...