Synthesis and biological activity of arylamides of 2-methylnicotinic and 2-phenylindolizine-8-carboxylic acids

…, NV Semyakina, VS Zalesov, ME Konshin

Index: Sigova, V. I.; Semyakina, N. V.; Zalesov, V. S.; Konshin, M. E. Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 3 p. 174 - 177 Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 3 p. 159 - 163

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Abstract

Compounds (la-f) can be used as starting materials for the preparation of indolizines. Indolizines with substituents in the pyridine ring have received little attention; the corresponding nitro-compounds are known [3], and in the last decade the ethoxycarbonyl derivatives have been examined in detail [5]. It has been found that 8- ethoxycarbonylindollzines are not converted into amides when their solutions are kept ...