Sulfonic acid functionalized silica as an efficient heterogeneous recyclable catalyst for one??pot synthesis of 2??substituted benziimidazoles

…, BS Kanth, KR Reddy, AS Kumar

Index: Das, Biswanath; Kanth, Boddu Shashi; Reddy, Kongara Ravinder; Kumar, Avula Satya Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1499 - 1502

Full Text: HTML

Citation Number: 28

Abstract

Benzimidazole nucleus has a ubiquitous presence in several bioactive molecules and is considered to be the 'privileged sub-structure'for drug design [1]. Various benzimidazole derivatives have been found to possess anticancer, antiviral and antihypertension properties [1-3]. Benzimidazoles are also important intermediates in organic synthesis [4, 5].