Tetrahedron

Study of mechanism of reduction of 2-bromo-1-(pX-phenyl) ethylidenemalononitrile by 1-benzyl-1, 4-dihydronicotinamide and 10-methyl-9, 10-dihydroacridine

YC Liu, B Li, QX Guo

Index: Liu, You-Cheng; Li, Bin; Guo, Qing-Xiang Tetrahedron, 1995 , vol. 51, # 35 p. 9671 - 9680

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Citation Number: 27

Abstract

The reduction of 2-bromo-1-(pX-phenyl) ethylidenemalononitrile (X-BPM: X= H, F, Cl, Br, CN) by NADH models BNAH and AcrH2 has been investigated. Based on product analysis, kinetic isotope effect, and free energy relationship, a direct hydride transfer and an electron