Synthesis and pharmacological properties of sydnocarb analogs with hydroxyl and carboxyl groups

…, ZA Olovyanishnikova, VG Yashunskii…

Index: Parshin, V. A.; Olovyanishnikova, Z. A.; Yashunskii, V. G.; Mashkovskii, M. D. Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 5 p. 333 - 337 Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 5 p. 54 - 58

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Abstract

The problem of the present investigation was the study of the influence of introducing certain hydrophiiic substituents into the benzene ring of the sydnocarb phenylcarbamoyl group on the central stimulant activity of the preparation. It seemed of interest to also study the influence on the activity of increasing the distance between the exocyclic nitrogen of the sydnonimine and the phenyl radical in this series of compounds.