Regioselective synthesis of (trifluoromethyl)-β-chloroenones

G Alvernhe, A Bensadat, A Ghobsi, A Laurent…

Index: Alvernhe, Gerard; Bensadat, Abdelkader; Ghobsi, Abdelkader; Laurent, Andre; Laurent, Eliane Journal of Fluorine Chemistry, 1997 , vol. 81, # 2 p. 169 - 172

Full Text: HTML

Citation Number: 11

Abstract

The regioselectivity of the conversion of 1, 3-diketones into β-chloroenones can be changed by the appropriate choice of the reagent: reaction with “Vilsmeier's reagent” prepared from POCl3, and dimethylformamide or treatment of the diketone with the oxalyl chloride in the presence of dimethylformamide.