Abstract 3-Acylamino-5-amino-1-R-1, 2, 4-triazoles are formed regioselectively on acylating 3, 5-diamino-1-R-1, 2, 4-triazoles with an equimolar amount of anhydrides, carboxylic acid chlorides, and sulfonyl chlorides. With an excess of anhydride and carboxylic acid chloride 3, 5-diacylamino-1-R-1, 2, 4-triazoles are formed. 3-Acylamino-5-amino-1-R-1, 2, 4-triazoles do not interact with sulfonyl chlorides. The higher reactivity of the 3-amino group towards ...
