6-Methoxy4-(a-di-n-hexylaminomethy 1)-quinolinolinemethanol (sX-2F172)~ prepared by King and Work4 by treatment of 6-methoxy-4-bromoacetylquinoline with di-n-hexylamine, followed by reduction of the ketone, was shown to possess antimalarial activity and it was desired to resynthesize it for further pharmacological testing. Since King ant1 Work had found that the synthesis did not proceed smoothly, a model experiment was first carried ...
